⚠️ Mechanism
Licorice may reduce warfarin efficacy through unknown mechanism.
📋 Effect
Possible decreased INR
💊 Management
Monitor INR. Minor clinical concern at dietary levels.
Plain Language Summary
This combination is considered a minor concern. Licorice may make warfarin less effective at preventing blood clots. Monitoring your blood clotting levels (INR) is recommended.
Source
Heck AM et al. Am J Health Syst Pharm 2000
Supporting Research
Effective licorice gargle juice for aphthous ulcer pain relief: A randomized double-blind placebo-controlled trial
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.