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Ginkgo × ADHD Medications

MODERATE Cyp-Inferred Evidence

Mechanism

Ginkgo is a weak inhibitor of CYP2D6, which decreases metabolism of CYP2D6 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect

Increased plasma levels of atomoxetine (adhd-medications), potentially leading to toxicity or enhanced adverse effects.

Management

Monitor for increased adverse effects of atomoxetine. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Plain Language Summary

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This combination carries a moderate risk because Ginkgo can slow down the way your body breaks down ADHD medications. This may cause the medication to build up in your system, which could increase the likelihood of experiencing side effects.

Source

Flockhart CYP450 Table (drug-interactions.medicine.iu.edu)

Research

Supporting Research

Ginkgo biloba for cognitive impairment and dementia
Ginkgo biloba for cognitive impairment and dementia
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Ginkgo biloba for tinnitus
Ginkgo biloba for intermittent claudication
The Comparative Efficacy of Multiple Interventions for Mild Cognitive Impairment in Alzheimer's Disease: A Bayesian Network Meta-Analysis
Comparative effects of Bacopa monnieri and Ginkgo biloba on cognitive functions: A systematic review and network meta-analysis
Ginkgo biloba for intermittent claudication
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Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications.