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Coq10 × Antihypertensives

MINOR INTERACTION — Possible Evidence

⚠️ Mechanism

CoQ10 may have mild blood pressure-lowering effects, potentially additive with antihypertensives.

📋 Effect

Possible additive blood pressure reduction

💊 Management

Monitor blood pressure. Generally a beneficial interaction.

Plain Language Summary

This combination is generally considered safe, but it may cause an extra drop in blood pressure. Because CoQ10 can also lower blood pressure, its effect may add to the power of your medication.

Source

Rosenfeldt FL et al. J Hum Hypertens 2007

Supporting Research

Cardioprotective interventions for cancer patients receiving anthracyclines PMID:21678342 DOI:10.1002/14651858.CD003917.pub4 2011
Cardioprotective interventions for cancer patients receiving anthracyclines PMID:18425895 DOI:10.1002/14651858.CD003917.pub3 2008
Efficacy and Safety of Coenzyme Q10 Supplementation in the Treatment of Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis PMID:35941510 DOI:10.1007/s43032-022-01038-2 2023
Coenzyme Q10 Supplementation Improves Adipokine Levels and Alleviates Inflammation and Lipid Peroxidation in Conditions of Metabolic Syndrome: A Meta-Analysis of Randomized Controlled Trials PMID:32375340 DOI:10.3390/ijms21093247 2020
Nutrition and bipolar disorder: a systematic review PMID:35608150 DOI:10.1080/1028415X.2022.2077031 2023
Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials PMID:36337001 DOI:10.1210/clinem/dgac585 2022
Interventions for the management of long covid (post-covid condition): living systematic review PMID:39603702 DOI:10.1136/bmj-2024-081318 2024
The efficacy and safety of coenzyme Q10 in Parkinson's disease: a meta-analysis of randomized controlled trials PMID:27830343 DOI:10.1007/s10072-016-2757-9 2017
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.