Calcium × Quinolones
MODERATE
Well-Established Evidence
Mechanism
Calcium chelates quinolone antibiotics, reducing absorption.
Effect
Reduced antibiotic absorption and efficacy
Management
Separate doses by at least 2 hours before or 6 hours after antibiotic.
Plain Language Summary
AI-generated · Qwen 3.6 · grounded in 2 sources · methodologyThis combination can interfere with your treatment because calcium can prevent your body from absorbing the antibiotic properly. When taken together, the calcium binds to the medicine, which may make the antibiotic less effective.
Source
FDA ciprofloxacin labeling
Research
Supporting Research
First-line drugs for hypertension
Beta-blockers for hypertension
Calcium channel blockers versus other classes of drugs for hypertension
Effect of early treatment with anti-hypertensive drugs on short and long-term mortality in patients with an acute cardiovascular event
Phlebotonics for venous insufficiency
Calcium channel blockers versus other classes of drugs for hypertension
Calcium supplementation for prevention of primary hypertension
Calcium supplementation for prevention of primary hypertension
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications.