⚠️ Mechanism
Interaction identified from DDInter 2.0 database. Specific drugs: Tizanidine
📋 Effect
See mechanism description
💊 Management
Consult healthcare provider before combining.
Plain Language Summary
This combination is considered dangerous due to a critical interaction. The data recommends consulting a healthcare provider before using caffeine and tizanidine together.
Source
DDInter 2.0 (ddinter.scbdd.com)
Supporting Research
The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials
Effects of caffeine chewing gum supplementation on exercise performance: A systematic review and meta-analysis
Genetic susceptibility to caffeine intake and metabolism: a systematic review
Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis
Caffeine, CYP1A2 Genotype, and Endurance Performance in Athletes
Caffeine and Cognitive Functions in Sports: A Systematic Review and Meta-Analysis
Effect of Acute Caffeine Intake on Fat Oxidation Rate during Fed-State Exercise: A Systematic Review and Meta-Analysis
The Effect of Acute Caffeine Ingestion on Endurance Performance: A Systematic Review and Meta-Analysis
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.