Caffeine × Iron Chelators
MODERATE
Ddinter-Verified Evidence
Mechanism
Interaction identified from DDInter 2.0 database. Specific drugs: Deferasirox, Deferasirox
Effect
See mechanism description
Management
Consult healthcare provider before combining.
Plain Language Summary
AI-generated · Qwen 3.6 · grounded in 2 sources · methodologyThis combination is considered moderately risky and may cause issues. Caffeine can interfere with how your body processes certain iron-removing medications. You should talk to your healthcare provider before using them together.
Source
DDInter 2.0 (ddinter.scbdd.com)
Research
Supporting Research
The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials
Effects of caffeine chewing gum supplementation on exercise performance: A systematic review and meta-analysis
Genetic susceptibility to caffeine intake and metabolism: a systematic review
Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis
Caffeine, CYP1A2 Genotype, and Endurance Performance in Athletes
Caffeine and Cognitive Functions in Sports: A Systematic Review and Meta-Analysis
Effect of Acute Caffeine Intake on Fat Oxidation Rate during Fed-State Exercise: A Systematic Review and Meta-Analysis
The Effect of Acute Caffeine Ingestion on Endurance Performance: A Systematic Review and Meta-Analysis
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications.