Caffeine × Fluoroquinolones Interaction

Mechanism

Interaction identified from DDInter 2.0 database. Specific drugs: Ciprofloxacin, Norfloxacin, Ciprofloxacin, Norfloxacin

Effect

See mechanism description

Management

Consult healthcare provider before combining.

Plain Language Summary

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This combination may not be safe for everyone because it can increase the effects of caffeine in your system. This could lead to more noticeable side effects, such as jitteriness or a rapid heartbeat.

Source

DDInter 2.0 (ddinter.scbdd.com)

Research

Supporting Research

The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials

PMID:30335479 DOI 2019

Effects of caffeine chewing gum supplementation on exercise performance: A systematic review and meta-analysis

PMID:35239468 DOI 2023

Genetic susceptibility to caffeine intake and metabolism: a systematic review

PMID:39438936 DOI 2024

Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis

PMID:36615805 DOI 2022

Caffeine, CYP1A2 Genotype, and Endurance Performance in Athletes

PMID:29509641 DOI 2018

Caffeine and Cognitive Functions in Sports: A Systematic Review and Meta-Analysis

PMID:33800853 DOI 2021

Effect of Acute Caffeine Intake on Fat Oxidation Rate during Fed-State Exercise: A Systematic Review and Meta-Analysis

PMID:38257100 DOI 2024

The Effect of Acute Caffeine Ingestion on Endurance Performance: A Systematic Review and Meta-Analysis

PMID:29876876 DOI 2018

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Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications.