⚠️ Mechanism
Caffeine may impair insulin sensitivity and raise blood glucose acutely.
📋 Effect
Possible mild increase in blood glucose
💊 Management
Monitor blood glucose. Moderate caffeine intake is generally safe.
Plain Language Summary
This combination is generally considered safe in moderation. However, caffeine may cause a slight, temporary increase in your blood sugar levels.
Source
Keijzers GB et al. Diabetes Care 2002
Supporting Research
The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials
Effects of caffeine chewing gum supplementation on exercise performance: A systematic review and meta-analysis
Genetic susceptibility to caffeine intake and metabolism: a systematic review
Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis
Caffeine, CYP1A2 Genotype, and Endurance Performance in Athletes
Caffeine and Cognitive Functions in Sports: A Systematic Review and Meta-Analysis
Effect of Acute Caffeine Intake on Fat Oxidation Rate during Fed-State Exercise: A Systematic Review and Meta-Analysis
The Effect of Acute Caffeine Ingestion on Endurance Performance: A Systematic Review and Meta-Analysis
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.