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5-HTP With Vitamin B6 50 mg

product on market Capsule The Vitamin Shoppe Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

L-5-Hydroxytryptophan is a precursor to serotonin with moderate evidence supporting its use for mood and sleep. Vitamin B6 acts as a cofactor in the synthesis of neurotransmitters. Research indicates these ingredients are generally well-tolerated when used as directed.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP With Vitamin B6 50 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mg (588% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Dicalcium Phosphate Gelatin Microcrystalline Cellulose Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take one (1) capsule up to twice daily, preferably with meals.

Warnings & Precautions

Warning: Do not use this product if you are pregnant or nursing or taking any antidepressant medications such as selective serotonin reuptake inhibitors (SSRI’s), tricyclic antidepressants or monamine oxidase inhibitors (MAOI). Consult your physician prior to use if you have any medical condition or are taking any medications.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

Formulation Notes

5-HTP with Vitamin B6 50mg

Gluten free Dairy free Soy free Nut free

Does Not Contain: Corn, wheat, gluten, sugar, salt, soy, starch, dairy, citrus, fish, preservatives, artificial colors or flavors.

Additional Information

Specialty Mood

Actual size

Store in a cool, dry place.

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

Item No. VS-1691 1319948 DR 37

Metadata

Product Details

UPC / SKU7 66536 01691 4
DSLD Entry Date2017-10-21
Product TypeOther Combinations
FormCapsule
BrandThe Vitamin Shoppe
DSLD ID79806
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
View all evidence for Vitamin B6 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.