🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 20% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

This formula contains Cascara Sagrada and Triphala, which have moderate evidence for promoting bowel movements. Milk thistle is included for liver support, though clinical evidence for its general efficacy remains limited. The overall evidence coverage for this specific ingredient profile is very low.

AI-generated summary based on research evidence. Not medical advice.

Product Label

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Label Data

3 Capsule(s) Serving Size
30 Servings
Botanical Product Type
20% Evidence Coverage

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
Cascara Sagrada
400 mg
Soothing Proprietary Blend (Herb/Botanical)
300 mg
Triphala Proprietary Extract Blend
270 mg
📊 Market median: 250.0mg (562 products) 📚 55 studies (Tier A: 0, B: 19)
This product: 190mg

Other Ingredients

Cellulose plant-derived Capsule

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Children 4 or More Years of Age Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Recommendation: Adults and Children Age 12 years and Over: take 2 to 3 capsules at bedtime with a full glass (8 ounces) of water. Do not take more than 2 to 3 capsules in a 24-hour period.

For a comprehensive, tri-phase internal detox, periodically use the Thisilyn Cleanse 15-day kits.

⚠️ Warnings & Precautions

Notice: This product contains Cascara sagrada. Read and follow directions carefully. Do not use if you have or develop diarrhea, loose stools or abdominal pain because Cascara sagrada may worsen these conditions and be harmful to your health.

Consult your physician if you have frequent diarrhea, or if you are pregnant, nursing, taking any medications or have a medical condition.

Caution: Do not use when nausea or vomiting are present unless recommended by a healthcare professional. Consult a healthcare professional if you notice a sudden change in bowel habits that persist over 2 weeks. Rectal bleeding or failure to move bowels after use may indicate a serious condition. Discontinue use and consult a healthcare professional.

Keep out of reach of children.

Safety sealed with printed outer shrink-wrap and inner seal. Do not use if either is broken or missing.

Do not take more than 2 to 3 capsules in a 24-hour period.

Not recommended for children under 12 years of age.

Do not take for more than 10 days as frequent or prolonged use may result in dependence. Do not exceed recommended dosage. Not for long term use.

🧪 Formulation Notes

Notice: This product contains Cascara sagrada.

Gluten free. No sugar, salt, yeast, wheat, soy, dairy products, artificial colors, flavors or preservatives.

Thisilyn Digestive Cleanse also contains a unique blend of peppermint, fennel, ginger and marshmallow to comfort the digestive tract during the cleansing process.

Herbal blend with Cascara sagrada Triphala & Thisilyn Milk thistle extract

Vegetarian

Additional Information

See outer carton for additional information.

Store in a cool, dry place.

LN15404.A01 BLK8242A

Herbal blend For toxin elimination and occasional constipation

Soothing action.

Detoxification. A combination of various herbs that help support liver health through elimination of toxins from the body.

#1 selling milk thistle brand

With digestive cleansers

Superior cleansing power Soothing blend

LBN15404.A01 BLK8242A

Spins milk thistle ingredient brands report; 52 wks ending 7/12/15; ttI US X-WF

Vegetarian

Product Details

UPC / SKU 0 33674 15404 5
DSLD Entry Date 2017-10-21
Product Type Botanical
Form Capsule
Brand Nature's Way
DSLD ID 79228
Data Updated 2026-04-11

Research Evidence

69 Research Sources
55 Avg Quality Score
34 Meta Analysis
26 Systematic Review
5 Rct
3 Clinical Trial
1 Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024
View all evidence for Milk Thistle →

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