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Silybin

product on market Capsule Integrative Therapeutics Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Silybin, derived from Silybum marianum, is researched for its potential to support liver health and protect hepatocytes from toxins. Current clinical evidence for these effects is generally considered limited to moderate. The ingredient profile maintains a high safety rating for typical use.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Silybin
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Cellulose Vegetable Capsule Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendations: Take 1 capsule once or twice daily, or as recommended by your healthcare professional.

Warnings & Precautions

If pregnant, nursing, or taking prescription drugs, consult your healthcare professional prior to use.

Formulation Notes

Contains no sugar, salt, yeast, wheat, gluten, corn, dairy products, artificial coloring, artificial flavoring, preservatives, or ingredients of animal origin.

Additional Information

LZ78436.A01 (BLK843A)

Metadata

Product Details

UPC / SKU8 71791 00266 1
DSLD Entry Date2017-10-21
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
BrandIntegrative Therapeutics
DSLD ID77828
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.