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Milk Thistle

product on market Liquid Indiana Botanic Gardens Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Milk thistle extract contains silymarin, which research suggests may support liver function and protect against certain toxins. However, the available evidence for these effects is generally considered limited or mixed. Total carbohydrates serve as a filler and do not provide therapeutic benefits.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Milk Thistle
Open Full PDF View on NIH DSLD →
Details

Label Data

1 mL
Serving Size
Botanical
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Glycerin Water
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement, take 1 mL (approx. 28 drops) two times daily, in a small amount of water.

Best if used by date on bottle.

Shake well.

Warnings & Precautions

Warning: If you are taking any medications or are pregnant or nursing do not use prior to consulting a physician.

Use only if seal is unbroken

Keep out of reach of children

Formulation Notes

Alcohol free liquid extract

Additional Information

Store in a dry, cool place.

Metadata

Product Details

UPC / SKU7 03308 20068 3
DSLD Entry Date2017-09-21
Product TypeBotanical
FormLiquid
DSLD ID77025
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.