Home/ Supplements/ Milk Thistle/ Milk Thistle 250 mg

Milk Thistle 250 mg

product on market Capsule Nature's Bounty Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Milk thistle seed extract contains silymarin, which is researched for its potential to support liver health and protect hepatocytes. However, the overall strength of clinical evidence for its efficacy in treating liver disease remains limited. This ingredient profile is generally considered safe for most users.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Milk Thistle 250 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Rice Flour Dicalcium Phosphate Gelatin Contains Less Than 2% of
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: For adults, take one (1) capsule three times daily, preferably with meals. Capsules may be opened and prepared as a tea.

Warnings & Precautions

WARNING: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Avoid this product if you are allergic to ragweed or daisy-like flowers.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Formulation Notes

Non-GMO, No Artificial Color, No Artificial Flavor, No Artificial Sweetener, No Preservatives, No Sugar, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast, No Fish. Sodium Free.

Additional Information

Over 40 years of trusted quality At Nature’s Bounty, we are committed to your health. For over 40 years we have been making trusted products, backed by science, and made with only the purest ingredients...guaranteed. So you can get the most out of life every day. Guaranteed Quality Laboratory Tested

Nutrition Questions or Comments? Call 1-800-433-2990 Mon.- Sat. 9 AM - 7 PM ET Join our Loyalty Program at NaturesBountyRewards.com

Standardized Extract Promotes Healthy Liver Function* HERBAL HEALTH

Store at room temperature.

Prod. No. 4549 08E B4548

Made In The USA with select ingredients from around the world

Metadata

Product Details

UPC / SKU0 74312 04549 3
DSLD Entry Date2016-06-24
Product TypeBotanical
FormCapsule
DSLD ID62149
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
Compare

Similar Products

View all Milk Thistle products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.