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Milk Thistle Extra Strength

product on market Capsule Yerba Prima Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Milk thistle seed extract contains silymarin, which is researched for its potential to support liver function and protect hepatocytes. There is moderate evidence suggesting its effectiveness in managing certain liver conditions. The ingredient profile maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Milk Thistle Extra Strength
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Bioperine Black Pepper extract Cellulose USP Kosher Gelatin Capsule
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

SUGGESTED ADULT USAGE: Normal use: 1 or 2 capsules daily, with or between meals. Intensive use: 3 capsules daily.

Warnings & Precautions

SAFETY SEALED: Do not use this product if printed band around cap or seal under cap is broken or missing.

CAUTION: Do not take capsules if you have difficulty in swallowing.

If you are taking medication or are under a doctor’s care, consult a health professional before use.

California residents only: Proposition 65 WARNING: This product contains a chemical known to the State of California to cause cancer and birth defects or other reproductive harm. For more information about Prop 65, see www.yerbaprima.com.

Formulation Notes

Yerba Prima Milk Thistle Extra Strength contains a patented milk thistle seed extract 4 times more bioavailable than Silymarin.

Contains Bioperine for maximum absorption.

Additional Information

Store at room temperature. Keep lid tightly closed to protect from humidity.

Note: Most herbal products, and most agricultural products, contain some chemicals that the plants absorb from the soil.

Made in U.S.A.

2013 457E

Supports Liver Health*

Just once daily

Yerba Prima Milk Thistle supports normal liver function and protects the liver against alcohol, chemicals, pollution and other harmful substances.*

Metadata

Product Details

UPC / SKU0 46352 00457 0
DSLD Entry Date2016-03-24
Product TypeBotanical
FormCapsule
DSLD ID58022
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.