Home/ Supplements/ Electrolytes/ 100% Pure L-Histidine

100% Pure L-Histidine

product on market Powder NutraBio Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

L-Histidine is an essential amino acid involved in the production of histamine and various proteins. Research evidence regarding its specific benefits for general health is limited. This ingredient is generally recognized as safe for consumption when taken in recommended dosages.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 100% Pure L-Histidine
Open Full PDF View on NIH DSLD →
Details

Label Data

0.5 Gram(s)
Serving Size
300
Servings
Amino acid/Protein
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)

Other Ingredients

Absolutely None
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

1-2 servings Mixed with 8-16 oz. Favorite beverage 1-2x daily between meals Suggested Use: As a dietary supplement, take 1-2 servings up to two times daily between meals, or as directed by your physician.

Warnings & Precautions

There are no reported side effects with L-Histidine, but overly high levels of it may lead to stress and mental disorders such as anxiety. People with schizophrenia have been found to have high levels of L-Histidine.

Warning: NOT INTENDED FOR USE BY PERSONS UNDER THE AGE OF 18. KEEP OUT OF THE REACH OF CHILDREN.

If you are pregnant, breast feeding, have known medical conditions (including kidney or liver disease) or are taking prescription or OTC medication(s) consult with your health care practitioner before using this product.

People suffering from schizophrenia or bipolar (manic) depression should not take an L-Histidine supplement without the approval of their medical professional.

Formulation Notes

ALLERGEN FREE

ALLERGEN FREE ~ NON-GMO ~ GLUTEN FREE ~ BSE/TSE FREE

No fillers No excipients No additives

Free of harmful inpurities

Additional Information

Manufactured in a GMP & FDA inspected facility

Made in a GMP & FDA inspected facility

Pharmaceutical Grade Free Form Amino Acid

Pharmaceutical Grade HPLC Lab Tested for Potency

Powder 300 servings

TRUE LABEL FULL LABEL DISCLOSURE

OU

STORE IN A COOL DRY PLACE.

SERVING SCOOP INCLUDED (MAY SETTLE TO THE BOTTOM DURING SHIPPING.)

24220-009 B20213-002

Metadata

Product Details

UPC / SKU6 49908 24220 6
DSLD Entry Date2015-09-25
Product TypeAmino acid/Protein
FormPowder
BrandNutraBio
DSLD ID51064
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.