Nighttime

product on market Other (e.g. tea bag) Estroven Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 25% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Melatonin and calcium are supported by moderate to strong evidence for improving sleep quality and bone health. Isoflavones and the herbal blend may assist with menopausal symptoms, though research on these specific botanical combinations is often limited. The overall ingredient profile is associated with a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Nighttime
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Caplet(s)
Serving Size
24
Servings
Other Combinations
Product Type
25%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
175 mg (20% DV)
2 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)
Isoflavones
60 mg
Estroven Herbal Sleep & Relaxation Blend
240 mg

Other Ingredients

Microcrystalline Cellulose Stearic Acid Croscarmellose Sodium Magnesium Stearate Silica Vanilla Essence Sweet Orange Essence Coating
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: Take one (1) caplet before bedtime. For best results, nightly use is important.

Warnings & Precautions

As with any dietary supplement, please inform your healthcare professional before taking.

Do not take if pregnant, breastfeeding or intending to become pregnant.

Keep out of reach of children.

Do not operate a motor vehicle or machinery while taking this product.

Contains soy.

Formulation Notes

NOW WITH CLINICALLY PROVEN MELATONIN!

Multi-Symptom Menopause Relief: Hot Flashes & Night Sweats

Estroven Nighttime does not contain preservatives, yeast, wheat, gluten, lactose or animal products.

Melatonin clinically proven to help you fall asleep easier Soy Isoflavones clinically proven to help reduce hot flashes and night sweats Estroven Herbal Sleep & Relaxation Blend with Chamomile, Passionflower, Valerian and Hops

Estroven(R) Nighttime does not contain synthetic estrogen.

Contains soy.

Additional Information

Helps You Fall Asleep Easier

PLUS Sleep

SAFE & EFFECTIVE

Only Estroven has a full line of products each designed to reduce hot flashes and night sweats plus help with your most bothersome symptoms. Choose the solution that best meets your specific needs.

Store at room temperature. Do not expose to excessive heat, humidity or direct sunlight.

Contains Novasoy BRAND Soy Isoflavones

NEW & IMPROVED

TESTED FOR QUALITY & PURITY IN THE USA

Metadata

Product Details

UPC / SKU0 92961 01864 4
DSLD Entry Date2014-07-25
Product TypeOther Combinations
FormOther (e.g. tea bag)
DSLD ID35210
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.