Home/ Supplements/ Nac/ NAC 400 mg

NAC 400 mg

product on market Capsule Signature Supplements Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

N-Acetyl Cysteine is a precursor to glutathione that supports antioxidant defenses and respiratory health. There is strong evidence supporting its use in managing mucus secretion and oxidative stress. This ingredient profile is generally well-tolerated with a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for NAC 400 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
50
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 600.0mg (7 products) 39 studies (A:2, B:13)

Other Ingredients

Cellulose Diatomaceous Earth
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For adults, take one (1) to two (2) capsules daily, preferably with a meal.

Warnings & Precautions

Keep out of reach of children.

Do not take this product within 2 hours of taking medications or follow the advice of your health care providers.

Warning: Pregnant or lactating women should consult a doctor before using any product. Consult doctor before use if you have, or have had, kidney disease, if you are on a magnesium-restricted diet or if you are taking any medications or remedies such as those to treat high blood pressure, heart medications, muscle relaxants or diuretics.

Discontinue use and consult your doctor if any adverse reactions occur, such as gastrointestinal discomfort or low blood pressure.

Not intended for use by persons under the age of 18

Formulation Notes

No: chemical fillers or binders, artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat.

From a GMP facility

N-Acetyl L-Cysteine

Powerful antioxidant support

Additional Information

Store in a dry place and avoid excessive heat.

Metadata

Product Details

DSLD Entry Date2025-09-25
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID338854
Data Updated2026-04-11
Research

Research Evidence

41
Research Sources
51
Avg Quality
19
Rct
13
Meta Analysis
9
Clinical Trial
B N-acetylcysteine as an adjuvant therapy for Helicobacter pylori eradication
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
B Effect of high-dose N-acetylcysteine on exacerbations and lung function in patients with mild-to-moderate COPD: a double-blind, parallel group, multicentre randomised clinical trial
Rct Nature communications 2024 PubMed DOI
B N-acetylcysteine for non-paracetamol (acetaminophen)-related acute liver failure
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Influence of N-acetylcysteine on chronic bronchitis or COPD exacerbations: a meta-analysis
Meta Analysis European respiratory review : an official journal of the European Respiratory Society 2015 PubMed DOI
B A randomised controlled trial of a mitochondrial therapeutic target for bipolar depression: mitochondrial agents, N-acetylcysteine, and placebo
Rct BMC medicine 2019 PubMed DOI
B Efficacy of N-acetylcysteine for patients with depression: An updated systematic review and meta-analysis
Meta Analysis General hospital psychiatry 2024 PubMed DOI
B Cysteine, cystine or N-acetylcysteine supplementation in parenterally fed neonates
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B N-acetylcysteine as an adjunctive treatment for bipolar depression: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Bipolar disorders 2021 PubMed DOI
B N-acetylcysteine as an adjunctive treatment for bipolar depression and major depressive disorder: a systematic review and meta-analysis of double-blind, randomized placebo-controlled trials
Meta Analysis Psychopharmacology 2020 PubMed DOI
B N-acetylcysteine Treatment in Chronic Obstructive Pulmonary Disease (COPD) and Chronic Bronchitis/Pre-COPD: Distinct Meta-analyses
Meta Analysis Archivos de bronconeumologia 2024 PubMed DOI
View all evidence for Nac →
Compare

Similar Products

View all Nac products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.