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Vitamin B6 250 mg

product on market Capsule Life Extension Safety: 60/100
60/100

Review before taking

  • Vitamin B6: 250mg is 2.5× the Tolerable Upper Intake Level (100mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Vitamin B6 supports neurotransmitter synthesis and metabolic functions, with strong evidence for its role in overall cellular health. However, the high dosage of 250 mg may pose safety concerns regarding potential nerve toxicity with long-term use. Evidence coverage for this specific formulation remains very limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vitamin B6: 250mg is 2.5× the Tolerable Upper Intake Level (100mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because it contains 250mg of Vitamin B6, which is 2.5 times higher than the recommended maximum daily limit of 100mg.

Label

Product Label

Label for Vitamin B6 250 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetarian Capsule(s)
Serving Size
100
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

250 mg (14706% DV)
Exceeds UL by 2.5× (UL: 100 mg) 114 studies (A:3, B:35)

Other Ingredients

Cellulose Microcrystalline Cellulose Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take one (1) capsule daily with food, or as recommended by a healthcare practitioner.

Warnings & Precautions

Read the entire label and follow the directions carefully prior to use.

Caution: Some people have reported temporary symptoms of peripheral neuropathy (tingling, numbness, sensation, decreased sensation to touch or balance difficulties) when taking vitamin B6 in doses above 300 mg daily, especially if the nutrient is taken without other B complex vitamins. This vitamin should not be taken without co-ingestion of equivalent doses of other B-complex vitamins.

Consult your physician before taking this vitamin if you are taking levodopa (L-dopa).

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Formulation Notes

Gluten free Non GMO LE Certified

Promotes cardiovascular health

Additional Information

Non GMO LE Certified

Store tightly closed in a cool, dry place.

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Metadata

Product Details

UPC / SKU7 37870 15351 1
DSLD Entry Date2025-05-21
Product TypeVitamin
FormCapsule
DSLD ID328793
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.