🟢 90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 25% of ingredients have research evidence
B Label Compliance Grade

Product Label

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

4 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
25% Evidence Coverage

Supplement Facts — Evidence Check

2.3 mg (100% DV)
✅ Within RDA (1.0× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 2.3mg UL 11mg
📊 Market median: 1000.0mg (2 products)
This product: 1500mg
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 216mg
Proprietary Cartilage Blend
40 mg

Other Ingredients

Microcrystalline Cellulose Hypromellose Corn Starch, Modified Titanium Dioxide Polyethylene Glycol Glycerin Magnesium Silicate Magnesium Stearate Croscarmellose Sodium Silicon Dioxide

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (100% of products) Structure/Function (74% of products) Nutrient (37% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

4 tiny pills a day

Directions: Adults take four (4) tablets once a day with a meal or two (2) tablets twice daily with meals.

⚠️ Warnings & Precautions

Keep out of reach of children. Not suitable for use by anyone under the age of 18 years old.

Not for use by pregnant or breastfeeding women. If on prescribed medication, consult your physician before use.

Protected with a tamper evident seal. Do not use if seal under cap is broken or missing.

🧪 Formulation Notes

Undenatured Type II collagen is derived from poultry source.

Type II Collagen Uniflex MSM Manganese Uniflex (FruiteX-B Calcium Fructoborate) is clinically proven to deliver faster comfort than glucosamine & chondroitin.

Clinically proven joint comfort 4 in 1 Joint Cartilage Bone Connective tissue 1.Undenatured Type II Collagen. 2.Based on data from two 14-day clinical research publications comparing Calcium Fructoborate to placebo with continued use (Pietrzkowski, Z., et al., Clin Interv Aging, 2014); and Glucosamine & Chondroitin to placebo (Reyes-Izquierdo, T., et al., J Aging Res Clin Pract, 2014).

Additional Information

For information call: 1-800-526-6251

Store in a cool, dry place with lid tightly closed.

Product Details

DSLD Entry Date 2025-05-21
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 328321
Data Updated 2026-04-11

Research Evidence

11 Research Sources
47 Avg Quality Score
7 Rct
2 Meta Analysis
1 Regulatory Source
C Trace elements and Alzheimer dementia in population-based studies: A bibliometric and meta-analysis
Meta Analysis Environmental pollution (Barking, Essex : 1987) 2023
C Proteins involved in iron metabolism in beef cattle are affected by copper deficiency in combination with high dietary manganese, but not by copper deficiency alone
Rct Journal of animal science 2010
C Reducing mineral usage in feedlot diets for Nellore cattle: II. Impacts of calcium, phosphorus, copper, manganese, and zinc contents on intake, performance, and liver and bone status
Rct Journal of animal science 2017
C Copper, Ceruloplasmin, Zinc, and Manganese Levels in Brain and Biological Fluids from Parkinson's Disease Patients: Systematic Review and Meta-Analysis
Meta Analysis Cells 2026
C Risedronate reverses bone loss in postmenopausal women with low bone mass: results from a multinational, double-blind, placebo-controlled trial. BMD-MN Study Group
Rct The Journal of clinical endocrinology and metabolism 2000
C Dietary Reference Intakes: Manganese
Regulatory Source IOM/NAM Dietary Reference Intakes 2000
C Vitamins and minerals intake adequacy in hematopoietic stem cell transplant: results of a randomized controlled trial.
Rct Bone marrow transplantation
C Collagen Peptides, in Association with Vitamin C, Sodium Hyaluronate, Manganese and Copper, as Part of the Rehabilitation Project in the Treatment of Chronic Low Back Pain.
Rct Endocrine, metabolic & immune disorders drug targets
C Glucosamine, chondroitin, and manganese ascorbate for degenerative joint disease of the knee or low back: a randomized, double-blind, placebo-controlled pilot study
Rct Military medicine 1999
C Effects of a cream containing madecassoside, 5% panthenol, and copper-zinc-manganese on improving postlaser resurfacing wound healing: A split-face, randomized trial.
Rct Dermatologic therapy
View all evidence for Manganese →

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