Manganese 50 mg by NaturesPlus — Ingredients, Evidence & Safety

Product Label

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Safety Alerts

⚠️ Manganese: 50mg is 4.5× the Tolerable Upper Intake Level (11mg)

This product received a low score because the amount of manganese provided is 4.5 times higher than the recommended maximum daily limit.

Label Data

1 Tablet(s) Serving Size

90 Servings

Mineral Product Type

0% Evidence Coverage

Supplement Facts — Evidence Check

Manganese

50 mg (2174% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 4.5× (UL: 11 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 50mg UL 11mg

Other Ingredients

Microcrystalline Cellulose Cellulose Stearic Acid Dicalcium Phosphate Silica Magnesium Stearate Pharmaceutical Glaze

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (74% of products) Nutrient (37% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: One tablets daily.

⚠️ Warnings & Precautions

Keep out of reach of children.

High-Potency Manganese - consult you doctor or qualified healthcare practitioner before taking.

🧪 Formulation Notes

Manganese promotes protein and fat metabolism, energy production, healthy nerves, immune defenses and blood sugar regulation. It also supports the formation of cartilage and synovial fluid of the joints, promotes normal bone growth and supports healthy reproductive functions.

Overall Wellness

Manufactured with the Biotron Process of amino acid chelation.

Vegetarian

Free from synthetic: colors, preservations. Gluten Free

Additional Information

Keep tightly closed in a cool, dry place.

Product Details

UPC / SKU 0 97467 03450 1

DSLD Entry Date 2024-08-22

Product Type Mineral

Form Tablet or Pill

Brand NaturesPlus

DSLD ID 318928

Data Updated 2026-04-11

Research Evidence

11 Research Sources

47 Avg Quality Score

7 Rct

2 Meta Analysis

1 Regulatory Source

C Trace elements and Alzheimer dementia in population-based studies: A bibliometric and meta-analysis

Meta Analysis Environmental pollution (Barking, Essex : 1987) 2023

PubMed DOI

C Proteins involved in iron metabolism in beef cattle are affected by copper deficiency in combination with high dietary manganese, but not by copper deficiency alone

Rct Journal of animal science 2010

PubMed DOI

C Reducing mineral usage in feedlot diets for Nellore cattle: II. Impacts of calcium, phosphorus, copper, manganese, and zinc contents on intake, performance, and liver and bone status

Rct Journal of animal science 2017

PubMed DOI

C Copper, Ceruloplasmin, Zinc, and Manganese Levels in Brain and Biological Fluids from Parkinson's Disease Patients: Systematic Review and Meta-Analysis

Meta Analysis Cells 2026

PubMed DOI

C Risedronate reverses bone loss in postmenopausal women with low bone mass: results from a multinational, double-blind, placebo-controlled trial. BMD-MN Study Group

Rct The Journal of clinical endocrinology and metabolism 2000

PubMed

C Dietary Reference Intakes: Manganese

Regulatory Source IOM/NAM Dietary Reference Intakes 2000

C Vitamins and minerals intake adequacy in hematopoietic stem cell transplant: results of a randomized controlled trial.

Rct Bone marrow transplantation

PubMed DOI

C Collagen Peptides, in Association with Vitamin C, Sodium Hyaluronate, Manganese and Copper, as Part of the Rehabilitation Project in the Treatment of Chronic Low Back Pain.

Rct Endocrine, metabolic & immune disorders drug targets

PubMed DOI

C Glucosamine, chondroitin, and manganese ascorbate for degenerative joint disease of the knee or low back: a randomized, double-blind, placebo-controlled pilot study

Rct Military medicine 1999

PubMed

C Effects of a cream containing madecassoside, 5% panthenol, and copper-zinc-manganese on improving postlaser resurfacing wound healing: A split-face, randomized trial.

Rct Dermatologic therapy

PubMed DOI

View all evidence for Manganese →