Sleep-Assure

product on market Tablet or Pill NaturesPlus 🟢 Safety: 100/100
Brand: NaturesPlus
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Bi-Layered Tablet(s) Serving Size
60 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Herbal Blend
25 mg
Gamma-Aminobutyric Acid
10 mg
5 mg
📊 3.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 5mg UL 100mg
3 mg
📊 Market median: 3.0mg (984 products) 📚 236 studies (Tier A: 2, B: 109)
This product: 3mg UL 10mg

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Stearic Acid Hydroxypropyl Methylcellulose Magnesium Stearate Cellulose Silica

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) No Allergies Gluten Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, one tablet 30 minutes before retiring.

⚠️ Warnings & Precautions

Notice: For adult use only. Keep out of reach of children.

Melatonin should not be used except with a physician's advice in the following conditions-pregnancy, lactation, serious illness, autoimmune disorders, diabetes, depression, endocrine disorders or during use of antidepressants or other prescription medications.

Do not drive or operate heavy machinery while using.

🧪 Formulation Notes

Nutritional support for healthy sleep and overall well-being.

Micro-gel sustained release system Rapid release/Sustained release with botanical extracts & essential cofactors

Vegetarian

Gluten Free

Free form synthetic: colors, preservatives. Free from milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy and sesame.

Additional Information

Keep tightly closed in a cool, Dry place.

Product Details

UPC / SKU 0 97467 04760 0
DSLD Entry Date 2024-09-25
Product Type Other Combinations
Form Tablet or Pill
Brand NaturesPlus
DSLD ID 318922
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI Cochrane
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
PubMed Cochrane
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
PubMed DOI
View all evidence for Vitamin B6 →

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