Liver DTX Complex by Shaklee — Ingredients, Evidence & Safety

Product Label

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Label Data

3 Caplet(s) Serving Size

30 Servings

Botanical Product Type

20% Evidence Coverage

Supplement Facts — Evidence Check

Calories

5 Calorie(s)

Total Carbohydrates

1 Gram(s) (1% DV)

Sodium

5 mg (1% DV)

Milk Thistle Seed Extract

300 mg

📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)

This product: 300mg

DTX Enhanced Proprietary Blend

900 mg

Other Ingredients

Maltodextrin Microcrystalline Cellulose Acacia Gum Croscarmellose Sodium

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Kosher Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take 3 caplets daily.

⚠️ Warnings & Precautions

Caution: If pregnant, nursing, or taking prescription medications, consult your physician prior to use.

Seal under cap for your protection. See bottom for exp. date.

Manufactured in a facility that may also process tree nuts, milk, egg, soy, wheat, shellfish, and fish.

🧪 Formulation Notes

With milk thistle seed extract, reishi mushroom, turmeric & artichoke to protect liver cells from toxins and oxidative stress and maintain healthy bile flow.

Gluten Free No artificial flavors, sweeteners, colors, or preservatives

V Vegan

Star-K (Kosher)

Protects liver cells from toxins and oxidative stress

Helps support liver cell function

Additional Information

V Vegan 100 % Carbon neutral Star-K (Kosher)

Dr Shaklee

Shaklee Since 1956 Safe Proven 100% Guaranteed

Product Details

DSLD Entry Date 2024-09-25

Product Type Botanical

Form Other (e.g. tea bag)

Brand Shaklee

DSLD ID 318617

Data Updated 2026-04-11

Research Evidence

69 Research Sources

55 Avg Quality Score

34 Meta Analysis

26 Systematic Review

5 Rct

3 Clinical Trial

1 Openfda Safety

A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease

Meta Analysis The Cochrane database of systematic reviews 2025

PubMed DOI Cochrane

B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis

Meta Analysis Japan journal of nursing science : JJNS 2024

PubMed DOI

B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications

Meta Analysis Asia Pacific journal of clinical nutrition 2025

PubMed DOI

B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases

Meta Analysis The Cochrane database of systematic reviews 2007

PubMed

B Pharmacotherapy for trichotillomania

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI

B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition ESPEN 2022

PubMed DOI

B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review

Meta Analysis Medicine 2024

PubMed DOI

B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury

Meta Analysis BMC complementary medicine and therapies 2025

PubMed DOI

B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis

Meta Analysis Medicine 2020

PubMed DOI

B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis

Meta Analysis Annals of hepatology 2024

PubMed DOI

View all evidence for Milk Thistle →