🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Softgel(s) Serving Size
120 Servings
Botanical Product Type
33% Evidence Coverage

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
Total Fat
0.5 Gram(s) (1% DV)
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 450mg

Other Ingredients

Bovine Gelatin Glycerin Water Caramel color Sunflower Oil Sunflower Lecithin Silicon Dioxide

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years) Kosher Halal Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Usage: Take 1 softgel daily.

⚠️ Warnings & Precautions

Caution: For adults only.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

🧪 Formulation Notes

Milk Thistle has been used by traditional herbalists for centuries. Clinical and non-clinical studies have indicated that Milk Thistle extract may help maintain healthy liver function through its ability to promote glutathione production, as well as by supporting the body’s normal detoxification processes.

Natural color variation may occur in this product.

NOW Extra Strength Silymarin has three times the milk thistle extract (450 mg per softgel) as in our regular strength product (150 mg per capsule).

Silymarin (360 mg)

Detox & liver support Promotes glutathione production Softgels for improved solubility

Non-GMO

Triangle K (Kosher) Contains gelatin

Triangle K (Kosher) Contains gelatin

Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or sesame ingredients.

Crescent H (Halal)

Made and quality tested in the USA with globally sourced ingredients.

Additional Information

Triangle K (Kosher) Contains gelatin

Botanicals/Herbs Family owned since 1968.

Store in a cool, dry place after opening.

GMP Quality Assured Crescent H (Halal)

This bottle is made from 100% PCR (post-consumer recycled) resin.

Product Details

UPC / SKU 7 33739 04785 4
DSLD Entry Date 2024-07-25
Product Type Botanical
Form Softgel Capsule
Brand NOW
DSLD ID 314318
Data Updated 2026-04-11

Research Evidence

69 Research Sources
55 Avg Quality Score
34 Meta Analysis
26 Systematic Review
5 Rct
3 Clinical Trial
1 Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024
View all evidence for Milk Thistle →

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