Silymarin 150 mg by Doctor's Best — Ingredients, Evidence & Safety

Product Label

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Label Data

2 Veggie Capsule(s) Serving Size

60 Servings

Non-Nutrient/Non-Botanical Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Silymarin

300 mg

📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)

This product: 300mg

Other Ingredients

Hypromellose Microcrystalline Cellulose Silicon Dioxide Magnesium Stearate

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested adult use: Take 2 capsules daily before a meal, or as recommended by a nutritionally informed physician.

⚠️ Warnings & Precautions

Warning: Consult a physician before use if you have a medical condition or are taking prescription medications.

Stomach discomfort may occur.

Avoid use if allergic to daisies, ragweed, or sunflower.

🧪 Formulation Notes

Silymarin has been traditionally used in Europe as an herbal remedy for a variety of ailments, with a focus on liver health. Silymarin refers to the active flavonoid components of milk thistle. Silymarin contains antioxidants that support healthy liver function, and support against free radicals.

Supports Healthy liver function Against free radicals

Supports healthy liver function

Vegan

Non-Gmo Gluten free Soy free

Additional Information

Store in a cool dry place.

Product Details

UPC / SKU 7 53950 00530 3

DSLD Entry Date 2023-12-14

Product Type Non-Nutrient/Non-Botanical

Form Capsule

Brand Doctor's Best

DSLD ID 302707

Data Updated 2026-04-11

Research Evidence

69 Research Sources

55 Avg Quality Score

34 Meta Analysis

26 Systematic Review

5 Rct

3 Clinical Trial

1 Openfda Safety

A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease

Meta Analysis The Cochrane database of systematic reviews 2025

PubMed DOI Cochrane

B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis

Meta Analysis Japan journal of nursing science : JJNS 2024

PubMed DOI

B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications

Meta Analysis Asia Pacific journal of clinical nutrition 2025

PubMed DOI

B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases

Meta Analysis The Cochrane database of systematic reviews 2007

PubMed

B Pharmacotherapy for trichotillomania

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI

B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition ESPEN 2022

PubMed DOI

B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review

Meta Analysis Medicine 2024

PubMed DOI

B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury

Meta Analysis BMC complementary medicine and therapies 2025

PubMed DOI

B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis

Meta Analysis Medicine 2020

PubMed DOI

B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis

Meta Analysis Annals of hepatology 2024

PubMed DOI

View all evidence for Milk Thistle →