🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Milk thistle seed extract contains silymarin, which is researched for its potential to support liver function and protect hepatocytes. Current clinical evidence for these effects is generally considered limited to moderate. The ingredient profile is associated with a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Product Label

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Label Data

1 Capsule(s) Serving Size
30 Servings
Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 250.0mg (562 products) 📚 55 studies (Tier A: 0, B: 19)
This product: 300mg
30 mg
📊 Market median: 250.0mg (562 products) 📚 55 studies (Tier A: 0, B: 19)
This product: 30mg

Other Ingredients

Rice Flour Cellulose Calcium Silicate

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested use: As a dietary supplement, take one (1) capsule one to two times daily, preferably with water.

⚠️ Warnings & Precautions

Warning: Keep out of reach of children.

Do not use if safety seal is damaged or missing.

If you are pregnant, nursing, taking any medications, have allergies to ragweed or daisy-like flowers, planning any medical procedure or have a medical condition, consult with your healthcare practitioner before use.

If you are pregnant, nursing, taking any medications, have allergies to ragweed or daisy-like flowers, planning any medical procedure or have a medical condition, consult with your healthcare practitioner before use.

🧪 Formulation Notes

Flavonolignans: The active constituents naturally present in authenticated milk thistle.

Gluten free

Advanced botanical fingerprint technology

Supplying 8 active consituents Standardized for silymarin

Vegan

Gluten-free

Additional Information

Store in a cool, dry place.

For product information, call (800) 439-2324.

Product Details

UPC / SKU 0 83000 16417 0
DSLD Entry Date 2023-08-23
Product Type Botanical
Form Capsule
DSLD ID 295428
Data Updated 2026-04-11

Research Evidence

69 Research Sources
55 Avg Quality Score
34 Meta Analysis
26 Systematic Review
5 Rct
3 Clinical Trial
1 Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024
View all evidence for Milk Thistle →

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DSLD ID: 295428 Fetched: 2026-04-11
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