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Indolplex with BR-DIM

product on market Tablet or Pill Integrative Therapeutics Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

The primary active component, BR-DIM, is a stabilized form of diindolylmethane used to support estrogen metabolism. Research evidence for these specific metabolic pathways is generally limited to moderate. Calcium and carbohydrates serve as supporting components with well-established safety profiles.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Indolplex with BR-DIM
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
Calcium
680 mg (52% DV)
Market median: 200.0mg (3 products) 11 studies (A:1, B:3)

Other Ingredients

Cellulose modified Food Starch Hypromellose Sodium Croscarmellose Silica Stearic Acid Magnesium Stearate Titanium Dioxide Tocophersolan Glycerin Phosphatidylcholine
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendation: Take 2 tablets daily with food, may reduce to 1 tablet daily with food, or as recommended by your healthcare professional.

Warnings & Precautions

Keep out of reach of children.

Safety sealed with printed inner seal. Do not use if seal is broken or missing.

Warning: Do not use this product if you are pregnant, nursing, or attempting to become pregnant.

A harmless but noticeable change in urine color may occur during usage of this product.

If taking any medications, consult a healthcare professional before use.

Formulation Notes

Vegan

Contains no wheat, soy, gluten, or dairy.

Bioavailable Diindolylmethane

Additional Information

For more information, please visit integrativepro.com

Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

Quality Global Sourcing Bottled & Tested In The USA

Metadata

Product Details

UPC / SKU8 71791 00146 6
DSLD Entry Date2023-07-18
Product TypeOther Combinations
FormTablet or Pill
DSLD ID288696
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
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A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.