🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
100 Servings
Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 250mg

Other Ingredients

Gelatin Rice Flour

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Recommended Use: Take 1 serving (1 capsule) with water or your favorite beverage twice daily on an empty stomach. Take first serving 30 minutes prior to breakfast. Take second 30 minutes prior to lunch. For added benefits drink 64 ounces of water daily.

⚠️ Warnings & Precautions

Warning: Pregnant or lactating women, diabetics, hypoglycemics, and people with known medical conditions and/or taking drugs should consult with a licensed physician and/or pharmacist prior to taking dietary supplements.

Do not use if seal is broken.

🧪 Formulation Notes

Antioxidants play an essential role in liver detox Milk Thistle Extract has been shown in numerous studies to support healthy liver function and has been used for over 2,000 years as a natural supplement for liver disorders. Silymarin is the main active ingredient in milk thistle and is both an anti-inflammatory and antioxidant.

Promote healthy liver Protect against free-radicals Support toxin removal Healthy regeneration

Help prevent cell damage Antioxidants protect your healthy cells from damaging free radicals. Free radicals are molecules that can cause damage to healthy cells and make them unstable.

High-Performance Liquid Chromatography (HPLC) Verified

Ultra pure ingredients Ultra micronized Max bioavailability Healthy liver function Detoxification & cleansing Boost immune function Natural ingredients

Silymarin is a standardized extract in milk thistle. Silibinin is the most active chemical in silymarin and is hypothesized to function by displacing toxins trying to bind to the liver, as well as by helping the liver to regenerate more quickly.

Additional Information

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Made in the USA

Health essentials

Pure nutrition Go green

Product Details

UPC / SKU 0 45635 77477 3
DSLD Entry Date 2023-06-22
Product Type Botanical
Form Capsule
DSLD ID 287418
Data Updated 2026-04-11

Research Evidence

69 Research Sources
55 Avg Quality Score
34 Meta Analysis
26 Systematic Review
5 Rct
3 Clinical Trial
1 Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024
View all evidence for Milk Thistle →

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