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Milk Thistle

product on market Capsule Kroeger Herb Products Co. Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Milk thistle seed extract contains silymarin, which is researched for its potential to support liver health and protect hepatic cells. There is moderate evidence suggesting its efficacy in managing certain liver conditions. Clinical data for general wellness use remains limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Milk Thistle
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
90
Servings
Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Vegetarian Source Capsules Water
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Directions: 1 capsule 3 times daily.

Warnings & Precautions

Do not purchase if seal is broken.

Keep out of reach of children.

Do not use during pregnancy unless recommended by your health care professional.

Formulation Notes

Complete Concentrates

Standardized to 80% silymarin using a full-profile, natural extraction in a base of raw Milk Thistle seed.

Only Complete Concentrates use standardized, full-profile herbal extracts of an all-natural water or water/alcohol extraction process without harmful solvents, such as acetone, hexane or denatured alcohol, and without excipients such as maltodextrin. Complete Concentrates are made with an active base of pure herb without any fillers, binders, or flowing agents.

Additional Information

Optima Valitudine "Excellent Health"

Metadata

Product Details

UPC / SKU6 96916 11507 7
DSLD Entry Date2023-01-23
Product TypeBotanical
FormCapsule
DSLD ID282505
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.