Milk Thistle by Kroeger Herb Products Co. — Ingredients, Evidence & Safety

Product Label

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Label Data

1 Capsule(s) Serving Size

90 Servings

Botanical Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Milk Thistle Seed Extract, Dried

185 mg

📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)

This product: 185mg

Milk Thistle seed extract

290 mg

📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)

This product: 290mg

Other Ingredients

Vegetarian Source Capsules Water

Label Claims — Verification

❓ All Other

All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Directions: 1 capsule 3 times daily.

⚠️ Warnings & Precautions

Do not purchase if seal is broken.

Keep out of reach of children.

Do not use during pregnancy unless recommended by your health care professional.

🧪 Formulation Notes

Complete Concentrates

Standardized to 80% silymarin using a full-profile, natural extraction in a base of raw Milk Thistle seed.

Only Complete Concentrates use standardized, full-profile herbal extracts of an all-natural water or water/alcohol extraction process without harmful solvents, such as acetone, hexane or denatured alcohol, and without excipients such as maltodextrin. Complete Concentrates are made with an active base of pure herb without any fillers, binders, or flowing agents.

Additional Information

Optima Valitudine "Excellent Health"

Product Details

UPC / SKU 6 96916 11507 7

DSLD Entry Date 2023-01-23

Product Type Botanical

Form Capsule

Brand Kroeger Herb Products Co.

DSLD ID 282505

Data Updated 2026-04-11

Research Evidence

69 Research Sources

55 Avg Quality Score

34 Meta Analysis

26 Systematic Review

5 Rct

3 Clinical Trial

1 Openfda Safety

A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease

Meta Analysis The Cochrane database of systematic reviews 2025

PubMed DOI Cochrane

B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis

Meta Analysis Japan journal of nursing science : JJNS 2024

PubMed DOI

B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications

Meta Analysis Asia Pacific journal of clinical nutrition 2025

PubMed DOI

B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases

Meta Analysis The Cochrane database of systematic reviews 2007

PubMed

B Pharmacotherapy for trichotillomania

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI

B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition ESPEN 2022

PubMed DOI

B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review

Meta Analysis Medicine 2024

PubMed DOI

B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury

Meta Analysis BMC complementary medicine and therapies 2025

PubMed DOI

B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis

Meta Analysis Medicine 2020

PubMed DOI

B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis

Meta Analysis Annals of hepatology 2024

PubMed DOI

View all evidence for Milk Thistle →