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Milk Thistle 50:1 Extract 400 mg

product on market Capsule Zazzee Naturals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Milk thistle seed extract contains silymarin, which is researched for its potential to support liver health and protect hepatocytes. There is moderate evidence suggesting it may assist in managing certain liver conditions. Clinical data for general wellness is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Milk Thistle 50:1 Extract 400 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Veggie Capsule(s)
Serving Size
200
Servings
Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Cellulose Rice, Powder Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested usage: Take 1 capsule once daily, preferably with food, or as directed by a healthcare practitioner.

Warnings & Precautions

Warnings: For adults only.

Consult physician if pregnant or nursing, taking medication, have allergies, or have a medical condition.

Consult a physician if pregnant or nursing, taking medication, have allergies, or have a medical condition. Avoid if allergic to other members of the aster family such as ragweed, daisy, marigolds and chrysanthemums.

Individuals with a sensitive stomach should take with food.

Keep out of reach of children.

Allergen information: Not manufactured with wheat, corn, gluten, soy, milk, egg, fish, shellfish, or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Keep in bottle.

Formulation Notes

Zazzee Naturals Milk Thistle Extract is an all-natural herbal supplement commonly used to promote healthy liver function. Our Milk Thistle is derived from a potent 50:1 extract equivalent to 20,000 mg of whole seed powder. Zazzee Milk Thistle is organically grown and verified to be authentic certified organic milk thistle extract, standardized to contain 80% silymarin flavonoids, equivalent to 320 mg per capsule.

Zazzee Milk Thistle is organically grown and verified to be authentic certified organic milk thistle extract, standardized to contain 80% silymarin flavonoids, equivalent to 320 mg per capsule.

Ultra strength potency, 20,000 mg equivalency Supports healthy liver function

Potent 50:1 extract, 80% silymarin Milk Thistle 50:1 extract 400 mg per capsule

Allergen information: Not manufactured with wheat, corn, gluten, soy, milk, egg, fish, shellfish, or tree nut ingredients.

Natural color variation may occur in this product.

Made with non-GMO ingredients

Additional Information

Store in a cool, dry place after opening.

Please recycle.

Good Manufacturing Practice GMP Consistent Quality Made in USA

Metadata

Product Details

UPC / SKUX0026D0GJF
DSLD Entry Date2022-10-24
Product TypeBotanical
FormCapsule
DSLD ID276104
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.