Pregnenolone 25 mg

product on market Tablet or Pill Source Naturals 🟢 Safety: 100/100
Brand: Source Naturals
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
120 Servings
Other Combinations Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
10 mg (12% DV)
25 mg
📊 Market median: 30.0mg (45 products)
Median 30.0mg This product: 25mg

Other Ingredients

Dibasic Calcium Phosphate Microcrystalline Cellulose Sorbitol Stearic Acid Silica Magnesium Stearate

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (100% of products) Structure/Function (58% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Directions: 1 tablet 1 to 2 times daily. 1/2 tablet may be sufficient for some people. Do not exceed 50 mg per day. Do not take for more than 30 days. Have your blood hormone (estrogen, testosterone, DHEA) levels regularly assessed by your physician. Using pregnenolone may elevate your DHEA levels, and DHEA can increase estrogen and testosterone levels. Read entire label before using.

⚠️ Warnings & Precautions

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Warning: Not for use by individuals under the age of 18 years.

Do not use if pregnant, may become pregnant, or breastfeeding. Consult a physician or licensed qualified health care professional before using this product if you have, or have a family history of, prostate cancer, prostate enlargement, heart disease, low "good" cholesterol (HDL), or if you are using any other dietary supplement, prescription drug, or over-the-counter drug.

Do not exceed recommended serving. Exceeding recommended serving may cause serious adverse health effects. Possible side effects include acne, hair loss, hair growth on the face (in women), aggressiveness, irritability, and increased levels of estrogen. Discontinue use and call a physician or licensed qualified health care professional immediately if you experience rapid heartbeat, dizziness, blurred vision, or other similar symptoms.

Do not exceed 50 mg per day. Do not take for more than 30 days. Have your blood hormone (estrogen, testosterone, DHEA) levels regularly assessed by your physician.

🧪 Formulation Notes

Pregnenolone 25 mg

Product Details

UPC / SKU 0 21078 00678 7
DSLD Entry Date 2022-10-24
Product Type Other Combinations
Form Tablet or Pill
Brand Source Naturals
DSLD ID 275398
Data Updated 2026-04-11

Research Evidence

9 Research Sources
38 Avg Quality Score
5 Rct
2 Narrative Review
2 Other
B Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans: A Randomized Clinical Trial
Rct JAMA network open 2020
PubMed DOI
C Pregnenolone Reduces Stress-Induced Craving, Anxiety, and Autonomic Arousal in Individuals with Cocaine Use Disorder
Rct Biomolecules 2022
PubMed DOI
C Pregnenolone for cognition and mood in dual diagnosis patients
Rct Psychiatry research 2010
PubMed DOI
C Reduced urine pregnenolone concentration after clinical response in patients with depression: An open-label short-term prospective study
Rct Psychoneuroendocrinology 2023
PubMed DOI
C Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia
Rct Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009
PubMed DOI
D Mitochondrial cytochrome P450 1B1 is involved in pregnenolone synthesis in human brain cells
Other The Journal of biological chemistry 2023
PubMed DOI
D Increased steroid hormone dehydroepiandrosterone and pregnenolone levels in post-mortem brain samples of alcoholics
Other Alcohol (Fayetteville, N.Y.) 2016
PubMed DOI
D Pregnenolone sulfate in the brain: a controversial neurosteroid
Narrative Review Neurochemistry international 2008
PubMed
D Individual differences in cognitive aging: implication of pregnenolone sulfate
Narrative Review Progress in neurobiology 2003
PubMed
View all evidence for Pregnenolone →

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