Home/ Supplements/ Milk Thistle/ Silymarin 300 mg

Silymarin 300 mg

product on market Capsule Metabolic Maintenance Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Silymarin is researched for its potential to support liver health by protecting hepatocytes from toxins. There is moderate evidence suggesting it may assist in managing certain liver conditions. This ingredient is generally well-tolerated with a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Silymarin 300 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

300 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Cellulose
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Directions: One (1) capsule daily, or as directed by a healthcare professional.

Warnings & Precautions

Caution: Pregnant or lactating women, consult your healthcare professional before taking this product.

Keep tightly closed in a cool, dry place, out of reach of children.

Formulation Notes

Egg free Gluten free Free of nuts Dairy free

Manufactured in a GMP Compliant Facility

Standardized Milk Thistle extract

Additional Information

Keep tightly closed in a cool, dry place, out of reach of children.

Metadata

Product Details

UPC / SKU8 38287 00304 5
DSLD Entry Date2022-07-21
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
BrandMetabolic Maintenance
DSLD ID274120
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
Compare

Similar Products

Milk Thistle
Sundown Naturals · Capsule
100
Milk Thistle 200 mg
GNC Herbal Plus · Capsule
100
Milk Thistle 175 mg
VitaCeutical Labs · Capsule
100
Milk Thistle
Douglas Laboratories · Capsule
100
Standardized Extract Milk Thistle 175 mg
Origin · Capsule
100
View all Milk Thistle products →
Milk Thistle research Best Milk Thistle All Milk Thistle products More from Metabolic Maintenance View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.