Home/ Supplements/ Electrolytes/ Calcium D-Glucarate 500 mg

Calcium D-Glucarate 500 mg

product on market Tablet or Pill Source Naturals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 25% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Calcium D-Glucarate is used to support the detoxification of glucuronidated toxins in the liver. Current research providing clinical evidence for these effects is limited. This formulation also provides a small amount of supplemental calcium to support general bone health.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Calcium D-Glucarate 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
60
Servings
Non-Nutrient/Non-Botanical
Product Type
25%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
Total Carbohydrates
1 Gram(s) (1% DV)
Calcium
124 mg (10% DV)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)

Other Ingredients

Sorbitol Stearic Acid modified Cellulose Gum Silica Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: 2 tablets with a meal three times daily. Additional benefits may be obtained by taking this product with antioxidants such as vitamins A, C, E and beta-carotene.

Warnings & Precautions

Warning: For adult use only.

Calcium D-glucarate may increase the body’s excretion of certain medications. If you are pregnant, may become pregnant, breastfeeding, or taking any prescription drug, consult your health care professional before using this product.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Formulation Notes

Cellular detoxifier

Source Naturals Calcium D-Glucarate includes the patented compound glucarate which has been shown in animal studies to support major detoxification pathways in the body. Calcium D-glucarate, the calcium salt of D-glucaric acid, is found naturally in the human body and in a variety of fruits and vegetables. Animal studies have shown that high doses of calcium D-glucarate may modulate beta-glucuronidase, and thereby support the process of glucuronidation. Glucuronidation is one of the body's healthy processes in which foreign organic compounds, fat-soluble toxins and excess steroid hormones such as estrogen are detoxified and excreted.

Metadata

Product Details

UPC / SKU0 21078 00871 2
DSLD Entry Date2022-08-23
Product TypeNon-Nutrient/Non-Botanical
FormTablet or Pill
BrandSource Naturals
DSLD ID272979
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Electrolytes →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.