Melatonin by Wholly Liquid — Ingredients, Evidence & Safety

Product Label

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Label Data

2 Spray(s) Serving Size

75 Servings

Non-Nutrient/Non-Botanical Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Melatonin

3 mg

📊 Market median: 3.0mg (984 products) 📚 236 studies (Tier A: 2, B: 109)

This product: 3mg UL 10mg

Other Ingredients

Water, Purified Vegetable Glycerin Citric Acid Natural flavor Potassium Sorbate Sunflower Lecithin Monk Fruit extract

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (86% of products) Nutrient (7% of products)

Target Groups

Adult (18 - 50 Years) No Allergies Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested Use: Shake bottle well before each use. Take two sprays per day or as directed by your healthcare professional.

⚠️ Warnings & Precautions

Warning: Consult your healthcare professional before use if you are pregnant, nursing, taking medications, have a known medical condition, or for any use by minors.

Do not use if safety seal is broken or missing.

Keep out of reach of children.

For nutritional use only.

🧪 Formulation Notes

Made in USA

Liquid sleep

Soy free Dairy free Sugar free Gluten free

Allergen free No artificial colors or sugars No synthetic fillers or binders

Additional Information

Storage Instructions: Store at room temperature away from direct sunlight. Keep tightly closed. For longer shelf life, refrigerate after opening.

Product Details

UPC / SKU WLMELA75

DSLD Entry Date 2022-08-23

Product Type Non-Nutrient/Non-Botanical

Form Liquid

Brand Wholly Liquid

DSLD ID 272110

Data Updated 2026-04-11

Research Evidence

291 Research Sources

55 Avg Quality Score

129 Meta Analysis

93 Systematic Review

51 Rct

11 Clinical Trial

2 Other

2 Regulatory Source

1 Openfda Safety

A Interventions for preventing delirium in hospitalised non-ICU patients

Meta Analysis The Cochrane database of systematic reviews 2016

PubMed DOI

A Melatonin for preoperative and postoperative anxiety in adults

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI Cochrane

A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials

Meta Analysis BMJ open 2022

PubMed DOI

B Pharmacological interventions for prevention of weight gain in people with schizophrenia

Meta Analysis The Cochrane database of systematic reviews 2022

PubMed DOI

B Melatonin for pre- and postoperative anxiety in adults

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Prevention of depression in adults with long-term physical conditions

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI

B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis

Systematic Review Lancet (London, England) 2022

PubMed DOI

B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis

Meta Analysis BMJ open 2023

PubMed DOI

B Second-generation antidepressants for preventing seasonal affective disorder in adults

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI

B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI

View all evidence for Melatonin →