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Serene Relaxation/Sleep Support

product on market Capsule 4 Organics Safety: 90/100
90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Calcium and magnesium are supported by moderate evidence for their roles in muscle relaxation and sleep regulation. However, the overall evidence coverage for this specific formulation is very limited. The product maintains a high safety score, indicating a low risk of adverse effects.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Serene Relaxation/Sleep Support
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
100 mg (25% DV)
100 mg (100% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
Proprietary Mix
600 mg

Other Ingredients

Magnesium Stearate Cellulose, Plant
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For general relaxation or stress relief, take 2 capsules on an empty stomach. As a sleep aid, take 4 capsules 45 minutes before bed. See warnings.

Warnings & Precautions

Warning: Due to the potency of this product, do not drive or operate machinery while taking.

Do not use if pregnant, or using any medication.

Keep out of reach of children.

Formulation Notes

Serene is a natural nutritional complex to help calm and soothe body and mind, and to promote deeper, more restful sleep. Take a half dose for relaxation, or a full dose as a sleep aid. Serene is a safe, effective, non-addictive sleep supplement free of unwanted side effects and next-day sluggishness.

Nutritional Relief For: Anxiety, stress, and nervousness Faster, deeper, more restful sleep Safe, non-addictive, no hangover

Made in the USA

Non-GMO Dietary Supplement

Metadata

Product Details

UPC / SKU8 50013 05906 5
DSLD Entry Date2022-07-21
Product TypeOther Combinations
FormCapsule
DSLD ID268158
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.