🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Capsule(s) Serving Size
Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 175mg

Other Ingredients

Maltodextrin Gelatin Contains Less Than 2% of

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: For adults, take one (1) capsule three times daily, preferably with meals. As a reminder, discuss the supplements and medications you take with your health care providers.

⚠️ Warnings & Precautions

Avoid this product if you are allergic to ragweed or daisy-like flowers.

WARNING: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

KEEP OUT OF REACH OF CHILDREN.

TAMPER RESISTANT: DO NOT USE IF SEAL UNDER CAP IS BROKEN OR MISSING.

Not intended for use by persons under the age of 18.

🧪 Formulation Notes

No yeast, wheat, gluten, milk or milk derivatives, lactose, sugar, preservatives, soy, artificial color, artificial flavor, sodium.

Additional Information

ACTUAL SIZE

helps support healthy liver function

{shield} ANTIOXIDANT SUPPORT

ANTIOXIDANT SUPPORT Milk Thistle seed extract helps maintain healthy liver function by rejuvenating liver cells. The benefits of this extract are due to antioxidant properties which help fight cell-damaging free radicals in the body. Free radicals may contribute to the premature aging of cells.

STORE AT ROOM TEMPERATURE AND AVOID EXCESSIVE HEAT.

ID201431

094 02 1394 PROD. NO. 11852 B11850 06C

Laboratory tested to meet strict quality control standards for potency, purity and disintegration.

Product Details

UPC / SKU 7 56880 11852 5
DSLD Entry Date 2013-12-24
Product Type Botanical
Form Capsule
Brand up&up
DSLD ID 26477
Data Updated 2026-04-11

Research Evidence

69 Research Sources
55 Avg Quality Score
34 Meta Analysis
26 Systematic Review
5 Rct
3 Clinical Trial
1 Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024
View all evidence for Milk Thistle →

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