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Centrum Sleep

product on market Capsule Centrum Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Melatonin and magnesium are supported by moderate to strong evidence for improving sleep onset and quality. The organic herbal and fruit blends have limited clinical data regarding their specific efficacy for sleep. The overall evidence coverage for this specific ingredient profile is very low.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Centrum Sleep
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

42 mg (10% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
3 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)
Organic Herbal Blend
150 mg
organic whole Fruit and Vegetable Blend
25 mg

Other Ingredients

organic Rice Flour Hypromellose L-Leucine Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults: Take 1 (one) capsule 30 minutes before bedtime, as needed, for occasional sleeplessness. Do not exceed suggested use. Not formulated for use in children.

Warnings & Precautions

Do not exceed suggested use.

Not formulated for use in children.

As with any supplement, if you are pregnant, nursing, or taking medication, including sleep medication, consult your doctor before use. Do not consume if pregnant or nursing.

Keep out of reach of children.

If taking other supplements, read label, since supplements may contain the same ingredient. Warnings Do not consume any alcohol while taking melatonin. Do not drive or operate heavy machinery while taking melatonin. Do not take other melatonin-containing products. Consult a healthcare professional if you are experiencing long-term sleep difficulties.

Bottle sealed with printed foil under cap. Do not use if foil is torn.

Formulation Notes

Whole food benefit blend Melatonin & botanicals

Melatonin helps support a healthy sleep cycle.

Chamomile, lemon balm & passionflower traditionally used to help soothe & relax.

Additional Information

Store at room temperature. Protect from heat, light, and moisture. Keep bottle tightly closed.

Questions? Comments? Call 1-877-CENTRUM (236-8786) For most recent product information, visit www.centrum.com

Metadata

Product Details

UPC / SKU3 0005 4477 60 6
DSLD Entry Date2021-11-19
Product TypeOther Combinations
FormCapsule
BrandCentrum
DSLD ID256990
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Electrolytes →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.