Silymarin

product on market Capsule Metabolic Maintenance Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Silymarin is researched for its potential to support liver health and protect hepatocytes from toxins. There is moderate evidence suggesting it may assist in managing certain liver conditions. However, overall evidence coverage for this specific formulation remains limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Silymarin
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

300 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Guar Gum vegetarian capsule
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

DIRECTIONS: One (1) capsule daily as a dietary supplement, or as directed by a Doctor.

Warnings & Precautions

CAUTION: Pregnant or lactating women, consult your healthcare professional before taking this product.

KEEP OUT OF THE REACH OF CHILDREN.

Formulation Notes

Excipient-free.

Standardized Milk Thistle Extract

Additional Information

STORAGE: Keep tightly closed in a dry place; do not expose to excessive heat.

Manufactured in a GMP Certified Facility

12646B EXP 1/13

V-10

Each preservative-free vegetarian capsule contains only the active ingredients listed on the label.

Metadata

Product Details

UPC / SKU8 38287 00304 5
DSLD Entry Date2013-08-23
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID25123
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.