Milk Thistle by Purely Beneficial — Ingredients, Evidence & Safety

Product Label

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Label Data

1 Capsule(s) Serving Size

120 Servings

Botanical Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

organic Milk Thistle 50:1 extract

500 mg

📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)

This product: 500mg

Other Ingredients

Methylcellulose Capsule

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Use: Take one (1) capsule daily, or as recommended by a healthcare provider.

⚠️ Warnings & Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

🧪 Formulation Notes

Vegan

Manufactured at an FDA registered facility Made in USA with global ingredients

Made with organic milk thistle

Extra strength 50:1 extract

Supports healthy liver detox

Does not contain: Fillers, artificial ingredients, GMO, preservatives, soy, gluten, dairy, gelatin, flavoring, coloring.

Additional Information

Good manufacturing practice GMP consistent quality

25K

100% Satisfaction guaranteed

Product Details

UPC / SKU 8 60004 19290 9

DSLD Entry Date 2021-08-23

Product Type Botanical

Form Capsule

Brand Purely Beneficial

DSLD ID 250041

Data Updated 2026-04-11

Research Evidence

69 Research Sources

55 Avg Quality Score

34 Meta Analysis

26 Systematic Review

5 Rct

3 Clinical Trial

1 Openfda Safety

A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease

Meta Analysis The Cochrane database of systematic reviews 2025

PubMed DOI Cochrane

B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis

Meta Analysis Japan journal of nursing science : JJNS 2024

PubMed DOI

B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications

Meta Analysis Asia Pacific journal of clinical nutrition 2025

PubMed DOI

B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases

Meta Analysis The Cochrane database of systematic reviews 2007

PubMed

B Pharmacotherapy for trichotillomania

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI

B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition ESPEN 2022

PubMed DOI

B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review

Meta Analysis Medicine 2024

PubMed DOI

B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury

Meta Analysis BMC complementary medicine and therapies 2025

PubMed DOI

B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis

Meta Analysis Medicine 2020

PubMed DOI

B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis

Meta Analysis Annals of hepatology 2024

PubMed DOI

View all evidence for Milk Thistle →