🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
60 Servings
Other Combinations Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 375mg

Other Ingredients

certified organic Acacia Vegetarian Capsule

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years) Kosher Organic Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Use: 1 capsule daily with or without food.

🧪 Formulation Notes

Liver health With 50 years of European research and over 100 clinical studies backing it, our patented, organic milk thistle extract is the trusted standard for supporting a strong liver and healthy detoxification. Plus, our SuperPUre processing ensures absolute purity, bioavailability and synergy.

Oregon Tilth Certified Organic (OTCO)

OU (Kosher) Certified Kosher

Non GMO

Made with organic milk thistle extract

No GMO's, dairy or gluten

Each capsule contains the equivalent of over 50,000 mg of freshly harvested, certified organic milk thistle seeds.

SuperPure

Additional Information

Oregon Tilth Certified Organic (OTCO) OU (Kosher) Certified Kosher

Product Details

UPC / SKU 8 52971 00436 1
DSLD Entry Date 2021-04-22
Product Type Other Combinations
Form Capsule
Brand Pure Synergy
DSLD ID 246621
Data Updated 2026-04-11

Research Evidence

69 Research Sources
55 Avg Quality Score
34 Meta Analysis
26 Systematic Review
5 Rct
3 Clinical Trial
1 Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024
View all evidence for Milk Thistle →

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