🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

📸

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Label Data

1 Tablet(s) Serving Size
60 Servings
Non-Nutrient/Non-Botanical Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

150 mg
📊 Market median: 30.0mg (45 products)
Median 30.0mg This product: 150mg

Other Ingredients

Micosolle Microcrystalline Cellulose Vegetable oil Vegetable Wax Cab-o-sil Magnesium Stearate Vitamin E

Label Claims — Verification

All Other
All Other (100% of products) Structure/Function (58% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use As a dietary supplement, 1 tablet daily with a meal or as directed by a health care professional.

⚠️ Warnings & Precautions

Warning: Not for use by individuals under the age of 18 years.

Do not use if pregnant or nursing. Consult a physician or licensed qualified health care professional before using this product if you have, or have a family history of, prostate cancer, prostate enlargement, heart disease, low "good" cholesterol (HDL), or if you are using any other dietary supplement, prescription drug, or over-the-counter drug.

Do not exceed recommended serving. Exceeding recommended serving may cause serious adverse health effects. Possible side effects include acne, hair loss, hair growth on the face (in women), aggressiveness, irritability, and increased levels of estrogen. Discontinue use and call a physician or licensed qualified health care professional immediately if you experience rapid heartbeat, dizziness, blurred vision, or other similar symptoms.

Keep out of reach of children.

Pregnenolone may affect levels of other hormones, such as progesterone, estrogen, testosterone, and/or DHEA. Do not take this product if you have a history of seizures. Do not take this product if you have breast cancer, prostate cancer, or other hormone-sensitive diseases. To report any adverse events call 1-800-332-1088.

🧪 Formulation Notes

Micronized, plant-sourced pregnenolone formulated in a lipid matrix to bypass the liver, with a particle size of less than 50 microns. Derived from non-irradiated and non-ethylene-oxide-treated wild yam.

Micronized Lipid Matrix Hypoallergenic

Additional Information

Keep in a cool, dry place, tightly capped

NutriCology Innovative Nutrition

Product Details

UPC / SKU 7 13947 52680 8
DSLD Entry Date 2020-09-25
Product Type Non-Nutrient/Non-Botanical
Form Tablet or Pill
Brand NutriCology
DSLD ID 235347
Data Updated 2026-04-11

Research Evidence

9 Research Sources
38 Avg Quality Score
5 Rct
2 Narrative Review
2 Other
B Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans: A Randomized Clinical Trial
Rct JAMA network open 2020
C Pregnenolone Reduces Stress-Induced Craving, Anxiety, and Autonomic Arousal in Individuals with Cocaine Use Disorder
Rct Biomolecules 2022
C Pregnenolone for cognition and mood in dual diagnosis patients
Rct Psychiatry research 2010
C Reduced urine pregnenolone concentration after clinical response in patients with depression: An open-label short-term prospective study
Rct Psychoneuroendocrinology 2023
C Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia
Rct Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009
D Mitochondrial cytochrome P450 1B1 is involved in pregnenolone synthesis in human brain cells
Other The Journal of biological chemistry 2023
D Increased steroid hormone dehydroepiandrosterone and pregnenolone levels in post-mortem brain samples of alcoholics
Other Alcohol (Fayetteville, N.Y.) 2016
D Pregnenolone sulfate in the brain: a controversial neurosteroid
Narrative Review Neurochemistry international 2008
D Individual differences in cognitive aging: implication of pregnenolone sulfate
Narrative Review Progress in neurobiology 2003
View all evidence for Pregnenolone →

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