Advanced Milk Thistle by Life Extension — Ingredients, Evidence & Safety

Product Label

📄 Open Full PDF View on NIH DSLD →

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Label Data

1 Softgel(s) Serving Size

60 Servings

Other Combinations Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Milk Thistle Phospholipid Proprietary Blend

760 mg

📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)

This product: 760mg

Siliphos Phytosome Milk Thistle extract

160 mg

📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)

This product: 160mg

Other Ingredients

Sunflower Oil Gelatin Glycerin purified Water Carob color Beeswax

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Read the entire label and follow the directions carefully prior to use. Directions: Take two (2) softgels daily, in divided doses, or as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Contains soybeans.

🧪 Formulation Notes

Gluten free Non GMO LE Certified

Additional Information

Store tightly closed in a cool, dry place.

Non GMO LE Certified

Advanced phospholipid delivery

Product Details

UPC / SKU 7 37870 19251 0

DSLD Entry Date 2020-08-23

Product Type Other Combinations

Form Softgel Capsule

Brand Life Extension

DSLD ID 232106

Data Updated 2026-04-11

Research Evidence

69 Research Sources

55 Avg Quality Score

34 Meta Analysis

26 Systematic Review

5 Rct

3 Clinical Trial

1 Openfda Safety

A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease

Meta Analysis The Cochrane database of systematic reviews 2025

PubMed DOI Cochrane

B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis

Meta Analysis Japan journal of nursing science : JJNS 2024

PubMed DOI

B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications

Meta Analysis Asia Pacific journal of clinical nutrition 2025

PubMed DOI

B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases

Meta Analysis The Cochrane database of systematic reviews 2007

PubMed

B Pharmacotherapy for trichotillomania

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI

B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition ESPEN 2022

PubMed DOI

B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review

Meta Analysis Medicine 2024

PubMed DOI

B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury

Meta Analysis BMC complementary medicine and therapies 2025

PubMed DOI

B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis

Meta Analysis Medicine 2020

PubMed DOI

B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis

Meta Analysis Annals of hepatology 2024

PubMed DOI

View all evidence for Milk Thistle →