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Diindolylmethane (DIM)

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100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Diindolylmethane (DIM) is researched for its role in modulating estrogen metabolism and supporting hormonal balance. Current evidence for these effects is generally considered limited to moderate. This ingredient profile maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Diindolylmethane (DIM)
Open Full PDF View on NIH DSLD →
Details

Label Data

100 mg
Serving Size
50
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 200.0mg (3 products) 11 studies (A:1, B:3)

Other Ingredients

None
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take 100 mg (1/16 tsp) to 200 mg (1/8 tsp) once or twice daily, or as directed by physician.

Warnings & Precautions

Warning: This product is not intended for use by those with a serious medical condition or pregnant or lactating women.

Consult with your physician before use.

Keep out of reach of children.

Formulation Notes

Free of: Sugar, soy, dairy, yeast, gluten, corn and additives.

Additional Information

For best results, refrigerate upon arrival. Storage: Keep dry, cool & dark

US Standard Measuring Spoons Spoon Size (level) milligrams 1/32 teaspoon 57 1/16 teaspoon 114 1/8 teaspoon 229

Metadata

Product Details

DSLD Entry Date2013-06-25
Product TypeNon-Nutrient/Non-Botanical
FormPowder
DSLD ID23079
Data Updated2026-04-11
Research

Research Evidence

5
Research Sources
44
Avg Quality
5
Rct
C A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen
Rct Breast cancer research and treatment 2017 PubMed DOI
C Phase Ib placebo-controlled, tissue biomarker trial of diindolylmethane (BR-DIMNG) in patients with prostate cancer who are undergoing prostatectomy
Rct European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2016 PubMed DOI
C Effectiveness of 3,3'-Diindolylmethane Supplements on Favoring the Benign Estrogen Metabolism Pathway and Decreasing Body Fat in Premenopausal Women
Rct Nutrition and cancer 2023 PubMed DOI
C The effects of light exposure on the cortisol stress response in human males.
Rct Stress (Amsterdam, Netherlands) PubMed DOI
D Pilot study: effect of 3,3'-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer
Rct Nutrition and cancer 2004 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.