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EstroBalance

product on market Tablet or Pill Nature's Way Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Calcium supports bone health and cellular function, while diindolylmethane is researched for its role in estrogen metabolism. Evidence for these ingredients is generally moderate, though the specific complex used here has limited clinical data. The profile maintains a high safety rating.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for EstroBalance
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
340 mg (26% DV)
Market median: 200.0mg (3 products) 11 studies (A:1, B:3)

Other Ingredients

Cellulose modified Food Starch Hypromellose Sodium Croscarmellose Silica Stearic Acid Magnesium Stearate Titanium Dioxide Tocophersolan Glycerin Phosphatidylcholine
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendation: Women take 1 tablet daily with food. If extra support is required, take 2 tablets with food.

Warnings & Precautions

Warning: Do not use this product if you are pregnant, nursing, or attempting to become pregnant.

A harmless but noticeable change in urine color may occur during usage of this product.

If you are taking any medications, consult a healthcare professional before use.

Keep out of reach of children.

Safety sealed with printed inner seal. Do not use if seal is broken or missing.

Formulation Notes

EstroBalance with absorbable BR-DIM Contains a unique, bioavailable form of BR-DIM

Promotes estrogen metabolism Supports breast health

1 Daily Dose = DIM from 2 lbs. of Broccoli

Gluten free. No yeast-derived ingredients, wheat, or dairy.

Vegetarian

Supports healthy estrogen metabolism

Women's health

The EstroBalance BR-DIM Advantage Why not get diindolylmethane from eating cruciferous vegetables? While eating cruciferous vegetables such as broccoli is recommended for good health, you'd have to eat at least two pounds of raw broccoli to obtain the DIM contained in just one daily dose of EstroBalance! 1 daily dose = DIM from 2 lbs. of broccoli! Why take EstroBalance with absorbable BR-DIM? Diindolylmethane, in supplement form, can be difficult to absorb, unless it's made with a special bioavailable form of diindolylmethane such as the BioResponse-DIM complex, as found in EstroBalance. Bio-Response-DIM complex provides an enhanced bioavailability delivery system for DIM so it's easy for the body to absorb.

The benefits of Diindolylmethane Supports healthy estrogen metabolism EstroBalance contains Indolplex diindolylmethane (BR-DIM), a phytonutrient found in cruciferous vegetables such as Brussels sprouts, broccoli and cabbage. BR-DIM has been shown to influence estrogen metabolism to increase the ratio of 2-hydroxyestrogen (2-OHE) to 16-hydroxyestrogen (16-OHE). 2-OHE is often referred to as the "good" estrogen metabolite and 16-OHE as a "bad" estrogen metabolite.

Promotes women's health

Increasing the ratio of 2-OHE to 16-OHE may have the following benefits: Reduces cyclical breast tenderness Promotes breast health Supports cardiovascular health Helps regulate healthy estrogen metabolism

EstroBalance with absorbable BR-DIM

Additional Information

The EstroBalance Advantage

Nature's Way since 1969

Metadata

Product Details

UPC / SKU7 63948 05333 9
DSLD Entry Date2020-07-23
Product TypeOther Combinations
FormTablet or Pill
DSLD ID230123
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.