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Milk Thistle 250 mg

product on market Capsule Natures Plus Herbal Actives Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Milk thistle is researched for its potential to support liver health and protect against oxidative stress. There is moderate evidence suggesting it may assist in managing certain liver conditions, though results across clinical trials remain mixed. The ingredient is generally recognized as safe for most users.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Milk Thistle 250 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

250 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Microcrystalline Cellulose Di-Calcium Phosphate Vegetable Cellulose Silica Magnesium Stearate purified Water
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement offering the consistent benefits of exact potency, one capsule daily or as recommended by your health care professional.

Warnings & Precautions

Note: If you are pregnant or nursing, consult your health care professional before using any herbal product.

Printed HerbaShield inner seal and full bottle seal. Do not use if either seal is missing or broken.

Keep out of reach of children.

Formulation Notes

Nutritional support for healthy liver function Guaranteed Maximum Potency: Each Herbal Actives formula is scientifically standardized to the highest level of active principles.

Each Herbal Actives Milk Thistle capsule, providing the greatest concentration of active botanical principles, maximizes the synergistic benefits of the whole seed, which naturally contains silybin, silydianin and silychristin.

This is not a prescription product. It is a dietary supplement made with the highest possible quality standards.

Milk Thistle 250 mg/80% Silymarin

Gluten free

Free from artificial colors and preservatives. Free from the common allergens yeast, wheat, corn, soy and milk.

Hypo-allergenic

Additional Information

HerbaShield: As exclusive purity and safety system including light-resistant bottle, airtight inner seal, moisture-absorbing packet, tamper-evident safety cap and tamper-proof neck seal.

HerbaShield

Guaranteed Maximum Potency

Prescription quality

Keep tightly closed in a cool, dry place.

Metadata

Product Details

UPC / SKU0 97467 07228 2
DSLD Entry Date2020-06-24
Product TypeBotanical
FormCapsule
DSLD ID228398
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.