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Milk Thistle Extract 250 mg

product on market Capsule Vital Nutrients Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Milk thistle seed extract contains silymarin, which is researched for its potential to support liver function and protect hepatocytes. Evidence for these effects is generally considered moderate, though clinical results vary across studies. This ingredient profile is associated with a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Milk Thistle Extract 250 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetarian Capsule(s)
Serving Size
30
Servings
Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Magnesium Citrate Cellulose Vegetable Cellulose Capsule Calcium Carbonate Leucine
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Recommendations 1 to 2 capsules 2 times daily, or as directed by your healthcare professional.

Warnings & Precautions

Keep out of reach of children

Use only if safety seal is intact

Warning If pregnant, consult your physician before taking.

Formulation Notes

Excludes coatings, binders, gluten (wheat, rye, barley), milk/dairy (casein, whey), soy protein, egg protein, sugar. Verified by independent testing

Raw materials and finished products are independently tested by U.S. labs. Learn more at vitalnutrients.net

Ethanol & water extract-no toxic solvents used, such as methanol, ethyl acetate, hexane, or acetone

Milk Thistle Extract (ethanol/water extract) 250 mg

Additional Information

Store sealed in a cool dry place

Metadata

Product Details

UPC / SKU6 93465 22811 1
DSLD Entry Date2020-06-24
Product TypeBotanical
FormCapsule
DSLD ID223346
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.