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Berberine Complex

product on market Capsule Integrative Therapeutics Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Barberry, Oregon Grape, and Goldenseal contain berberine, which has moderate evidence for supporting healthy blood glucose levels. Research suggests these botanical extracts may also influence lipid metabolism. However, overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Berberine Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
45
Servings
Botanical
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)
Goldenseal (Hydrastis canadensis) root and rhizome extract
100 mg

Other Ingredients

Hydroxypropyl Methylcellulose Cellulose Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendation: Take 2 capsules three times daily, or as recommended by your healthcare professional.

Warnings & Precautions

Keep out of reach of children.

Safety sealed with printed inner seal. Do not use if seal is broken or missing.

Warning: Do not use this product if you are pregnant or nursing. If you have diabetes or are taking prescription drugs, consult your healthcare professional prior to use.

Formulation Notes

Contains no salt, wheat, gluten, soy, dairy products, ingredients of animal origin, or artificial colors, flavors, or preservatives.

Intestinal support

Metadata

Product Details

UPC / SKU8 71791 00085 8
DSLD Entry Date2020-06-24
Product TypeBotanical
FormCapsule
BrandIntegrative Therapeutics
DSLD ID223040
Data Updated2026-04-11
Research

Research Evidence

98
Research Sources
55
Avg Quality
48
Systematic Review
39
Meta Analysis
4
Rct
4
Clinical Trial
1
Other
1
Narrative Review
1
Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 PubMed DOI
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019 PubMed DOI
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023 PubMed DOI
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024 PubMed DOI
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024 PubMed DOI
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019 PubMed DOI
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023 PubMed DOI
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025 PubMed DOI
View all evidence for Berberine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.