Home/ Supplements/ Electrolytes/ Formula 419 Protease + Cal-Mag

Formula 419 Protease + Cal-Mag

product on market Capsule NESS Nutritional Enzyme Support System Safety: 90/100
90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Calcium and magnesium are well-supported minerals for bone health and neuromuscular function. The proprietary enzyme blend's efficacy is less documented, reflecting the limited overall evidence coverage for this specific formulation. Research generally indicates these ingredients are safe for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Formula 419 Protease + Cal-Mag
Open Full PDF View on NIH DSLD →
Details

Label Data

4 Vegetarian Capsule(s)
Serving Size
22
Servings
Other Combinations
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
20 mg (2% DV)
4 mg (1% DV)
Market median: 500.0mg (1 products) 316 studies (A:8, B:159)
Proprietary Enzyme Blend
543 mg

Other Ingredients

Plant Fiber Water
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommended Use: Take four (4) capsules one or more times daily on an empty stomach, or as directed by your healthcare professional.

Warnings & Precautions

Caution: If you are pregnant, nursing, have a serious medical condition, or take any medications, consult your physician before use.

Use only if tamper evident seal is unbroken.

Keep out of reach of children.

Formulation Notes

Formulated exclusively for healthcare professionals NESS Protease + Cal-Mag is uniquely formulated to help support healthy neurological function.

Non-GMO

Vegetarian

GMP Compliant

Contains No: Aspartame, sugar, salt, gluten, artificial colors or flavors, dairy products, wheat, soy, yeast or corn proteins.

Additional Information

Store tightly closed in a cool, dry place.

Metadata

Product Details

UPC / SKU7 07636 03362 3
DSLD Entry Date2020-05-22
Product TypeOther Combinations
FormCapsule
DSLD ID221283
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.