🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Capsule(s) Serving Size
100 Servings
Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

500 mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 500mg

Other Ingredients

Gelatin Capsules

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use: Take 1 capsule, or as directed by a healthcare professional.

⚠️ Warnings & Precautions

Keep away from children.

Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.

If any adverse reactions occur, immediately stop using this product and consult your doctor. If seal under cap is damaged or missing, do not use.

🧪 Formulation Notes

Our products don't contain flow agents like magnesium stearate. Not now, not ever.

Supports liver function

Additional Information

Self Health Resource Center 1055 Bay Blvd., Ste A Chula Vista, CA 91911 Customer Service Toll Free: (866) DR-CLARK (372-5275) www.DrClarkStore.com

Made in USA

Leader in purity Established by Dr. Clark's family in 1993

GMP Quality Assured

Store at room temperature.

Company does not adopt any Dr. Clark claims.

Product Details

UPC / SKU 6 52384 10719 8
DSLD Entry Date 2020-05-22
Product Type Botanical
Form Capsule
DSLD ID 219984
Data Updated 2026-04-11

Research Evidence

69 Research Sources
55 Avg Quality Score
34 Meta Analysis
26 Systematic Review
5 Rct
3 Clinical Trial
1 Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024
View all evidence for Milk Thistle →

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