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Milk Thistle (Silymarin)

product on market Capsule Mason Natural Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Milk thistle contains silymarin, which has moderate evidence for supporting liver health and protecting hepatocytes. Calcium is essential for bone density and neuromuscular function. Overall, research evidence for this specific ingredient combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Milk Thistle (Silymarin)
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Botanical with Nutrients
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
65 mg (6% DV)
300 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Gelatin Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults - Take two capsules two times daily, preferably with food, as a dietary supplement.

Warnings & Precautions

Warning: No serious or significant adverse reactions or drug interactions have been reported to date with the use of Milk Thistle. A mild, laxative effect may occur in some individual and usually lasts for only 2 to 3 days.

If you are pregnant, nursing, taking any medications or planning any medical procedure, consult your physician before use.

Discontinue use and consult your physician if any adverse reactions occur.

Keep out of reach of children.

Tamper-evident seal: Do not use product if seal appears tampered.

Formulation Notes

Standardized extract May support Liver function

Contains naturally harvested herbal products. Color variation is possible.

Guaranteed no added: Sugar, sodium, yeast, soy, corn, wheat, starch, fragrances, dairy, egg, artificial colors and preservatives.

Soy free

Additional Information

Mason Guarantee Laboratory tested cGMP Certified Good Manufacturing Practice

N

Mason Natural Est. 1967

Store in a dry place under controlled room temperature: 20 degrees - 25 degrees C (68 degrees - 77 degrees F).

Metadata

Product Details

UPC / SKU3 11845 12995 6
DSLD Entry Date2020-04-23
Product TypeBotanical with Nutrients
FormCapsule
DSLD ID216867
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.