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Milk Thistle 500 mg

product on market Capsule Mason Natural Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Milk thistle contains silymarin, which is researched for its potential to support liver function and protect hepatocytes. There is moderate evidence suggesting it may assist in managing certain liver conditions. This ingredient is generally well-tolerated with a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Milk Thistle 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Gelatin Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults - Take one capsule, preferably with food, as a dietary supplement.

Warnings & Precautions

Warning: If you are pregnant, nursing, taking any medications or planning any medical procedure, consult your physician before use.

Discontinue use and consult your physician if any adverse reactions occur.

Keep out of reach of children.

Contains gluten.

Tamper-evident seal: Do not use product if seal appears tampered.

Formulation Notes

May support Liver function

Contains naturally harvested herbal products. Color variation is possible.

Guaranteed no added: Sugar, starch, soy, sodium, yeast, corn, wheat, dairy, egg, fish, tree nuts, peanuts, crustacean shellfish, artificial colors, fragrance, and preservatives.

Soy free

Whole herb

Additional Information

Mason Guarantee Laboratory tested cGMP Certified Good Manufacturing Practice

N

Est. 1967

Store in a dry place under controlled room temperature: 20 degrees - 25 degrees C (68 degrees - 77 degrees F).

Metadata

Product Details

UPC / SKU3 11845 11505 8
DSLD Entry Date2020-03-24
Product TypeBotanical
FormCapsule
DSLD ID216845
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.